potato germplasm

Examining Virus Elimination Techniques in Potato Germplasm

Plant viruses cause the second highest losses to crop yields every year, surpassed only by fungi. A research team in Norway recently compared several in vitro virus elimination therapies on a variety of potato cultivars. Traditional meristem culture, cryotherapy, and a combination of chemotherapy and thermotherapy techniques were included in this study and assessed for their ability to eliminate potato-specific

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Renal inflammatory pathway mediation by miRNA: isolation and quantification of miR-103a-3p

RNA isolation and quantification of miRNAs are gaining significance as promising methods in cancer biomarker discovery. Establishing standardized protocols for collection, sample storage conditions, and the use of exogenous and endogenous controls for normalization are all critical aspects to reliably quantify miRNA levels which can be further implemented in a clinical laboratory setting. Quilun et al. at the University of

Read More »

Exploring the role of cerebrospinal fluid miRNA in brain tumour diagnostics

The National Institute of Health estimates that approximately 6 in 100 000 individuals develop brain or central nervous system-related cancers each year1. Current approaches in the diagnosis of brain cancer include CT scans, MRI and tissue biopsy. However, such techniques can be limited by tumour location and heterogeneity, and in the case of tissue biopsy, its highly invasive nature. “Liquid

Read More »

ASTECs: Engineered Immortals that Package a Potent Punch

Cell therapy using cardiosphere-derived cells (CDCs) is an increasingly promising treatment for acute and congenital heart muscle injuries, including myocardial infarction (MI). The therapeutic potency of CDCs has been attributed to the cargo they secrete via exosomes and other extracellular vesicles (EVs), which act to suppress inflammatory and fibrotic processes, whilst promoting cell renewal. Unfortunately, broad clinical application of CDCs

Read More »
post

Norgen Biotek’s Stool Nucleic Acid Preservative Best-in-Class for Maintenance of Microbial Community Composition in Comparative Study

Large-scale human microbiota studies have generated key insights into a variety of disease processes, including cardiovascular disease, carcinogenesis, diabetes, hypertension, and inflammatory bowel disease. However, the utility of such studies is contingent on accurate and consistent representation of microbial communities. Stool preservatives are commonly used to prevent shifts in microbial community composition which result in bias during the period between

Read More »

The Detection & Expression of Circulating miRNAs as Biomarkers Hold High Clinical Implications for Predicting Prostate Cancer Recurrence Post Radical Prostatectomy.

Currently, there is limited technology available for accurately predicting high-risk cancer biochemical recurrence (BCR). As such, there is a significant clinical need to discover non-invasive biomarkers in hopes to identify these high-risk patients and prevent unnecessary therapy and over-treatment.  Researchers from Sunnybrook Research Institute aimed to identify non-invasive circulating miRNAs in patients that had previously undergone radical prostatectomy in order

Read More »

Webinar 2: Comprehensive Coverage of Exosome Purification and Exosomal RNA Isolation from Different Types of Liquid Biopsies

On April 17th and 18th, Norgen Biotek presented their second webinar: “Comprehensive Coverage of Exosome Purification and Exosomal RNA Isolation from Different Type of Liquid Biopsies”. Bastien Paré – a member of the R&D team, who works extensively with liquid biopsies, exosomes, RNA purifications, and small RNA NGS – facilitated the exosomal-related webinar in French and English. Topics included exosomal

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blood plasma

Researchers in Spain Identify Liver-Specific miRNAs Detected in Exosomes from HIV/HCV Patients

A group of researchers from the Institute of Health Carlos III (ISCIII) in Spain, presented a poster at the annual meeting for ISEV (International Society of Extracellular Vesicles) which analysed exosome RNA content for identification of new liver disease biomarkers. Using highthroughput NGS, the group identified multiple liver-specific miRNAs from plasma exosomes of patients who are coinfected with HIV and

Read More »

Nature Medicine: Researchers at University of California Identify Orphan Non-Coding RNA as a Promoter of Breast Cancer Metastasis

In a systematic search to identify breast-cancer-specific small non-coding RNAs, a group of researchers has discovered a novel microRNA found to be a promoter of breast cancer metastasis. They focused on this specific set of RNAs to search for a possible source of regulators capable of moderating disease pathways. They discovered 201 previously unknown small RNAs expressed solely in breast

Read More »

Molecular Med Tri-Con 2019

Norgen will be in San Francisco at the Molecular Med TRI-CON. Come by Booth #621 to visit with Norgen CEO Dr. Haj-Ahmad and Tom from Sales and Marketing. Details Conference: Molecular Med Tri-Con Date: March 10 – March 15, 2019 Booth: #621 Location: Moscone Center South, San Francisco, CA Conference Schedule < March 1March 08 – March 1415 March >

Read More »

Examining Virus Elimination Techniques in Potato Germplasm

Plant viruses cause the second highest losses to crop yields every year, surpassed only by fungi. A research team in Norway recently compared several in vitro virus elimination therapies on a variety of potato cultivars. Traditional meristem culture, cryotherapy, and a combination of chemotherapy and thermotherapy techniques were included in this study and assessed for their ability to eliminate potato-specific

Read More »

Renal inflammatory pathway mediation by miRNA: isolation and quantification of miR-103a-3p

RNA isolation and quantification of miRNAs are gaining significance as promising methods in cancer biomarker discovery. Establishing standardized protocols for collection, sample storage conditions, and the use of exogenous and endogenous controls for normalization are all critical aspects to reliably quantify miRNA levels which can be further implemented in a clinical laboratory setting. Quilun et al. at the University of

Read More »

Exploring the role of cerebrospinal fluid miRNA in brain tumour diagnostics

The National Institute of Health estimates that approximately 6 in 100 000 individuals develop brain or central nervous system-related cancers each year1. Current approaches in the diagnosis of brain cancer include CT scans, MRI and tissue biopsy. However, such techniques can be limited by tumour location and heterogeneity, and in the case of tissue biopsy, its highly invasive nature. “Liquid

Read More »

ASTECs: Engineered Immortals that Package a Potent Punch

Cell therapy using cardiosphere-derived cells (CDCs) is an increasingly promising treatment for acute and congenital heart muscle injuries, including myocardial infarction (MI). The therapeutic potency of CDCs has been attributed to the cargo they secrete via exosomes and other extracellular vesicles (EVs), which act to suppress inflammatory and fibrotic processes, whilst promoting cell renewal. Unfortunately, broad clinical application of CDCs

Read More »

Norgen Biotek’s Stool Nucleic Acid Preservative Best-in-Class for Maintenance of Microbial Community Composition in Comparative Study

Large-scale human microbiota studies have generated key insights into a variety of disease processes, including cardiovascular disease, carcinogenesis, diabetes, hypertension, and inflammatory bowel disease. However, the utility of such studies is contingent on accurate and consistent representation of microbial communities. Stool preservatives are commonly used to prevent shifts in microbial community composition which result in bias during the period between

Read More »

The Detection & Expression of Circulating miRNAs as Biomarkers Hold High Clinical Implications for Predicting Prostate Cancer Recurrence Post Radical Prostatectomy.

Currently, there is limited technology available for accurately predicting high-risk cancer biochemical recurrence (BCR). As such, there is a significant clinical need to discover non-invasive biomarkers in hopes to identify these high-risk patients and prevent unnecessary therapy and over-treatment.  Researchers from Sunnybrook Research Institute aimed to identify non-invasive circulating miRNAs in patients that had previously undergone radical prostatectomy in order

Read More »

Webinar 2: Comprehensive Coverage of Exosome Purification and Exosomal RNA Isolation from Different Types of Liquid Biopsies

On April 17th and 18th, Norgen Biotek presented their second webinar: “Comprehensive Coverage of Exosome Purification and Exosomal RNA Isolation from Different Type of Liquid Biopsies”. Bastien Paré – a member of the R&D team, who works extensively with liquid biopsies, exosomes, RNA purifications, and small RNA NGS – facilitated the exosomal-related webinar in French and English. Topics included exosomal

Read More »

Researchers in Spain Identify Liver-Specific miRNAs Detected in Exosomes from HIV/HCV Patients

A group of researchers from the Institute of Health Carlos III (ISCIII) in Spain, presented a poster at the annual meeting for ISEV (International Society of Extracellular Vesicles) which analysed exosome RNA content for identification of new liver disease biomarkers. Using highthroughput NGS, the group identified multiple liver-specific miRNAs from plasma exosomes of patients who are coinfected with HIV and

Read More »

Nature Medicine: Researchers at University of California Identify Orphan Non-Coding RNA as a Promoter of Breast Cancer Metastasis

In a systematic search to identify breast-cancer-specific small non-coding RNAs, a group of researchers has discovered a novel microRNA found to be a promoter of breast cancer metastasis. They focused on this specific set of RNAs to search for a possible source of regulators capable of moderating disease pathways. They discovered 201 previously unknown small RNAs expressed solely in breast

Read More »

Molecular Med Tri-Con 2019

Norgen will be in San Francisco at the Molecular Med TRI-CON. Come by Booth #621 to visit with Norgen CEO Dr. Haj-Ahmad and Tom from Sales and Marketing. Details Conference: Molecular Med Tri-Con Date: March 10 – March 15, 2019 Booth: #621 Location: Moscone Center South, San Francisco, CA Conference Schedule < March 1March 08 – March 1415 March >

Read More »